Aceclofenac SR 200 mg is an NSAID used to relieve pain and inflammation in arthritis-related conditions. It works by reducing inflammatory chemicals and should be taken as prescribed. If a dose is missed, take it soon unless it’s close to the next one. Do not stop without medical advice. 

Common side effects include nausea, diarrhea, and abdominal pain, while drowsiness is less frequent. Avoid during pregnancy and with alcohol or certain medicines. In case of overdose, symptoms like dizziness and vomiting require urgent medical help. Store in a cool, dry place, away from children. 

Aceclofenac 200 mg SR is an oral medicine belonging to the class of non-steroidal anti-inflammatory (NSAID) medicines. It is used for following indications: 

1. To treat pain caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. 

1. Take aceclofenac exactly as prescribed by your doctor, regularly at the same time each day. 
2. Do not stop taking aceclofenac without your doctor’s approval, even if you feel better. 
3. If you forget to take the medicine, take it as soon as you remember, unless it’s almost time for the next one, then just skip it. 

More Common

1. Nausea 
2. Vomiting 
3. Diarrhea 
4. Flatulence 
5. Constipation 
6. Dyspepsia 
7. Abdominal pain 
8. Crohn’s disease 

Less Common

1. Drowsiness 
2. Sleepiness 

Aceclofenac is a medicine that helps reduce swelling and pain. It works by blocking a protein COX-2, which lowers the amount of chemicals like PGE2, IL-1β, and TNF- these are things in your body that cause pain and swelling. It also stops certain white blood cells (called neutrophils) from sticking to blood vessels, which helps reduce more damage. Plus, it helps protect the soft tissue in your joints (called cartilage) by helping make something called glycosaminoglycan, which keeps your joints healthy. A part of this medicine, called 4′-hydroxyaceclofenac, also helps protect the cartilage by lowering harmful enzymes and keeping special cells called chondrocytes safe. 

1- Allergy/Hypersensitivity

If you have previously had an allergy to this medicine, inform your doctor.

2- Pregnancy

If you are pregnant or planning to conceive, inform your doctor, as this medicine is not safe during pregnancy, especially in the last trimester. 

Avoid taking aceclofenac 100 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal: 

Aceclofenac does not interact with any food products, but alcohol should be avoided before and after taking the medicine, as it can increase or decrease the effect of the drug. 

1. The medicine should be stored at room temperature  
2. Keep away from sunlight and moisture  
3. Keep away from the reach of children 

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

2-[2-[2-(2,6-dichloroanilino)phenyl]acetyl]oxyacetic acid 

Daily Dose

Take aceclofenac exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

If you know someone who takes this medicine and has symptoms like dizziness, confusion, and vomiting, then rush them to the hospital immediately

1- What are Aceclofenac and Paracetamol Tablets used For? 

The combination of Aceclofenac and Paracetamol is used for pain relief in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle and joint pain, toothaches, backaches, body aches, and high fever. 

2- What is Aceclofenac Tablet Used For? 

Aceclofenac is used to treat pain caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. 

3- Can Aceclofenac Be Used for Headaches? 

Yes, Aceclofenac can be used for headaches. A 100 mg dose may help relieve headache pain. 

4- Can Aceclofenac Be Used for Period Cramps? 

Yes, Aceclofenac tablets are used to treat menstrual cramp pain. A 100 mg dose may provide relief. 

1. Isiptalk. Aceclofenac and Paracetamol Tablet Uses [Internet]. [cited 2025 Mar 28]. Available from. 
2. Letzel H, Mégard Y, Lamarca R, Raber A, Fortea J. The efficacy and safety of aceclofenac versus placebo and naproxen in women with primary dysmenorrhoea. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2006 Dec 1;129(2):162-8. Available from. 
3. Iolascon G, Gimenez S, Mogyorosi D. A review of aceclofenac: analgesic and anti-inflammatory effects on musculoskeletal disorders. Journal of pain research. 2021 Nov 30:3651-63. Available from. 
4. DrugBank. Aceclofenac [Internet]. [cited 2025 Mar 28]. Available from.