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Diclofenac, Serratiopeptidase (pain Killer Tablet)

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Diclofenac, Serratiopeptidase (pain Killer Tablet)

Drug Code: 8

| tablettablet| Pack of 10 tablets
MRP ₹75

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Batch Details

Composition

diclofenac 50 mg + serratiopeptidase 10 mg

Batch

69|PGT26-0408A

Expiry

January 2028

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Batch Details

Composition

diclofenac 50 mg + serratiopeptidase 10 mg

Batch

69|PGT26-0408A

Expiry

January 2028

About Diclofenac 50 mg and Serratiopeptidase 10 mg

Diclofenac 50 mg and Serratiopeptidase. It is used to relieve pain, swelling, and inflammation in conditions such as joint pain, muscle pain, back pain, toothache, sports injuries, arthritis, and post-surgical pain and swelling.  

Diclofenac reduces pain and inflammation, while serratiopeptidase helps reduce swelling and promotes healing. It is best taken before or after food to reduce stomach irritation. Alcohol should be avoided because it may increase the risk of stomach problems and bleeding. People with allergies to painkillers, stomach ulcers, liver or kidney disease, heart disease, bleeding disorders, or asthma triggered by painkillers should not take this medicine without a doctor’s advice. 

Medicine Highlights

Uses 1. To treat muscle pain and swelling 
2. To treat back pain and neck pain 
3. To treat joint pain and toothache 
4. To treat sports injury pain 
5. To treat arthritis-related pain and swelling 
6. To treat post-surgery pain and swelling    
Common Side Effects  1. Nausea 
2. Vomiting 
3. Stomach pain / stomach upset 
4. Heartburn / acidity 
5. Diarrhea / loose motions 
6. Dizziness 
7. Headache 
8. Loss of appetite  
Additional Information To keep you safe and healthy, use this medicine only with your doctor’s guidance.
Storage 1. The medicine should be stored at room temperature.  
2. Keep away from sunlight and moisture.  
3. Keep away from the reach of children 
How to Take This MedicineTake this medication orally with a sip of water. 

Diclofenac 50 mg and Serratiopeptidase 10 mg Uses

Diclofenac 50 mg and Serratiopeptidase 10 mg is used to treat the following conditions: 

  1. Muscle pain and swelling 
  2. Back pain and Neck pain 
  3. Joint pain and Toothache 
  4. Sports injury pain 
  5. Arthritis-related pain and swelling 
  6. Post-surgery pain and swelling     

Diclofenac 50 mg and Serratiopeptidase 10 mg side effects

More Common

  1. Black stools or blood in stools 
  2. Vomiting blood 
  3. Severe stomach pain 
  4. Breathing difficulty / chest tightness 
  5. Swelling of face, lips, or throat 
  6. Severe skin rash / allergy 
  7. Unusual bruising or bleeding        

Less Common 

  1. Black stools or blood in stools (possible stomach bleeding) 
  2. Vomiting blood 
  3. Severe stomach pain 
  4. Swelling of face, lips, or throat 
  5. Breathing difficulty 
  6. Allergic skin reactions   

How Diclofenac 50 mg and Serratiopeptidase 10 mg works

Diclofenac 50 mg and Serratiopeptidase 10 mg work by reducing pain, swelling, and inflammation. Diclofenac blocks the production of prostaglandins, which are chemicals responsible for pain and inflammation. Serratiopeptidase is a proteolytic enzyme that breaks down inflammatory proteins and helps reduce swelling and fluid buildup at the affected site. Together, they provide effective relief from pain and inflammation while promoting faster recovery. 

Safety Measures and Warning

Allergy/Hypersentivity

People allergic to Diclofenac 50 mg and Serratiopeptidase 10 mg or any of its ingredients are not recommended to take this medicine as it may cause serious allergic reactions such as rash, swelling, or breathing difficulty.

Liver Problems

If you have liver disease, consult your doctor before taking this medicine because diclofenac may increase the risk of liver damage.

Kidney Problems

If you have kidney disease, consult your doctor before taking this medicine because it may worsen kidney function.

Heart Conditions

If you have heart disease or high blood pressure, consult your doctor before taking this medicine because it may increase the risk of fluid retention and cardiovascular complications.

Bleeding disorders

If you have bleeding disorders or are taking blood thinners, consult your doctor before taking this medicine as it may increase the risk of bleeding.

Asthma

If you have asthma, especially after taking painkillers, consult your doctor before taking this medicine because it may trigger breathing problems.

Pregnancy

If you are pregnant, consult your doctor before taking this medicine because it may affect the baby, especially during the last trimester.

Breastfeeding

 If you are breastfeeding, consult your doctor before taking this medicine because small amounts may pass into breast milk.

Diclofenac 50 mg and Serratiopeptidase 10 mg Interaction with Food Product

This medicine can be taken after food to help reduce stomach upset. It is best to avoid or limit alcohol while taking this medicine because it can increase the risk of stomach irritation, ulcers, and bleeding. Very spicy or oily foods may also worsen stomach discomfort in some people.

Diclofenac 50 mg and Serratiopeptidase 10 mg Interaction with Other Medicines

Avoid taking Diclofenac 50 mg and Serratiopeptidase 10 mg with the following medicines, as it may increase or decrease the desired effect, or in worse cases, it could be fatal:

Diclofenac 50 mg and Serratiopeptidase 10 mg Chemical Structure

IUPAC (International Union of Pure and Applied Chemistry)/ Chemical name

Diclofenac: 2-[2-(2,6-dichloroanilino)phenyl]acetic acid 

Diclofenac 50 mg

Serratiopeptidase: (11Z)-17-hydroxy-2-phenyl-9-oxa-1,5,14,21-tetrazatetracyclo[12.7.1.03,8.016,21]docosa-3(8),4,6,11,16,19-hexaene-15,18-dione  

Serratiopeptidase 10 mg

Intake routine/cycle

Daily dose

Take Diclofenac 50 mg and Serratiopeptidase 10 mg exactly as your doctor recommends. The dose may change based on your condition and how well you respond. Do not take more than prescribed without consulting your doctor.

Missed Dose

If you forget to take your medicine, take the medication as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. Always consult the doctor before making any changes to your dosage.

Overdose

It is not recommended to take more than the prescribed dose of Diclofenac 50 mg and Serratiopeptidase 10 mg, as overdose may cause severe stomach pain, nausea, vomiting, dizziness, stomach bleeding, breathing difficulty, kidney problems, or liver damage.

Storage

  1. Store the medicine at room temperature. 
  2. Keep away from sunlight and moisture. 
  3. Keep out of reach of children 

Directions for use

  1. Take Diclofenac 50 mg and Serratiopeptidase 10 mg exactly as prescribed by your doctor, at the same time each day. 
  2. Do not stop taking Diclofenac 50 mg and Serratiopeptidase 10 mg without your doctor’s approval, even if you feel better. 
  3. If you forget to take Diclofenac 50 mg and Serratiopeptidase 10 mg, take them as soon as you remember. If it’s almost time for your next dose, skip the missed dose.

FAQ’s

What are the uses of Diclofenac? 

Diclofenac is used to relieve pain, inflammation, and swelling in conditions such as arthritis, muscle and joint pain, back pain, injury-related pain, and menstrual pain. 

What is the mechanism of action of Diclofenac? 

 Diclofenac works by blocking cyclooxygenase (COX) enzymes, which reduces the production of prostaglandins responsible for pain, inflammation, and swelling. 

What is the drug class of Diclofenac? 

Diclofenac belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs), which help reduce pain, inflammation, and swelling. 

What are the side effects of Serratiopeptidase? 

Serratiopeptidase may cause nausea, vomiting, stomach discomfort, diarrhea, loss of appetite, skin rash, itching, and in rare cases, allergic reactions or increased risk of bleeding. 

What is the mechanism of action of Serratiopeptidase? 

Serratiopeptidase works by breaking down inflammatory proteins at the affected site, which helps reduce swelling, decrease pain, and promote faster healing. 

What is the drug class of Serratiopeptidase? 

Serratiopeptidase belongs to the class of proteolytic enzymes (anti-inflammatory enzyme agents). 

Can I use Serratiopeptidase during pregnancy? 

 Serratiopeptidase is not generally recommended during pregnancy due to limited safety data. It should be used only if clearly prescribed by a doctor after assessing the benefits and risks. 

Reference

  1. Diclofenac (Oral Route) Description and Brand Names – Mayo Clinic [Internet]. Available from 
  2. Alfaro RA, Modi PV. Diclofenac [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2023. Available from 
  3. Serrapeptase Uses, Benefits & Dosage Herbal Database [Internet]. Drugs.com. 2024. Available from 
  4. Jadhav SB, Shah N, Rathi A, Rathi V, Rathi A. Serratiopeptidase: Insights into the therapeutic applications. Biotechnology Reports. 2020 Dec;28:e00544.  
  5. PubChem. Serrapeptase [Internet]. Nih.gov. PubChem; 2026 [cited 2026 Feb 24]. Available from 
  6. SERRAPEPTASE: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews [Internet].  Available from    
Pranathi Chintaluri avatar

Written By-

Pranathi Chintaluri

Medical content writer

Doctor of Pharmacy | 2+ Year experience

Mahak Phartyal avatar

Reviewed By-

Mahak Phartyal

Medical Content writer and reviewer

Bachelors in Pharmacy | 3+ Year experience

Last Updated: 16 Jun 2026

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